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dc.contributor.authorSong, CE-
dc.contributor.authorLee, SW-
dc.contributor.authorRoh, EJ-
dc.contributor.authorLee, SG-
dc.contributor.authorLee, WK-
dc.date.accessioned2024-01-21T17:12:27Z-
dc.date.available2024-01-21T17:12:27Z-
dc.date.created2021-09-03-
dc.date.issued1998-03-27-
dc.identifier.issn0957-4166-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/143173-
dc.description.abstractA new synthetic route to (3R,4S)-3-hydroxy-4-phenylazetidin-2-one an important precursor for the paclitaxel side chain, has been developed using intramolecular cyclization of N-(p-methoxyphenyl) (2S,3R)-2-acetoxy-3-bromo-3-phenylpropionamide which can be easily obtained by catalytic asymmetric dihydroxylation of N-(p-methoxyphenyl)-trans-cinnamide, followed by bromoacetylation. (C) 1998 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectLACTAM SYNTHON METHOD-
dc.subjectALPHA-HYDROXY ACIDS-
dc.subjectENANTIOSELECTIVE SYNTHESIS-
dc.subjectASYMMETRIC DIHYDROXYLATION-
dc.subjectAMINO-ACIDS-
dc.subjectBETA-AMINO-
dc.subjectHETEROGENEOUS MEDIA-
dc.subjectHIGHLY EFFICIENT-
dc.subjectTAXOTERE-
dc.subjectN-BENZOYL-(2R,3S)-3-PHENYLISOSERINE-
dc.titleA new synthetic route to (3R,4S)-3-hydroxy-4-phenylazetidin-2-one as a taxol side chain precursor-
dc.typeArticle-
dc.identifier.doi10.1016/S0957-4166(98)00049-4-
dc.description.journalClass1-
dc.identifier.bibliographicCitationTETRAHEDRON-ASYMMETRY, v.9, no.6, pp.983 - 992-
dc.citation.titleTETRAHEDRON-ASYMMETRY-
dc.citation.volume9-
dc.citation.number6-
dc.citation.startPage983-
dc.citation.endPage992-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000072825200013-
dc.identifier.scopusid2-s2.0-0344269324-
dc.relation.journalWebOfScienceCategoryChemistry, Inorganic & Nuclear-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusLACTAM SYNTHON METHOD-
dc.subject.keywordPlusALPHA-HYDROXY ACIDS-
dc.subject.keywordPlusENANTIOSELECTIVE SYNTHESIS-
dc.subject.keywordPlusASYMMETRIC DIHYDROXYLATION-
dc.subject.keywordPlusAMINO-ACIDS-
dc.subject.keywordPlusBETA-AMINO-
dc.subject.keywordPlusHETEROGENEOUS MEDIA-
dc.subject.keywordPlusHIGHLY EFFICIENT-
dc.subject.keywordPlusTAXOTERE-
dc.subject.keywordPlusN-BENZOYL-(2R,3S)-3-PHENYLISOSERINE-
dc.subject.keywordAuthortaxol-
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