Recent Advances in Electrochemical and Nanophotonic Biosensors for SARS-CoV-2 Detection

Authors
Lee, Yeon KyungSong, Hyun Seok
Issue Date
2024-03
Publisher
한국바이오칩학회
Citation
BioChip Journal
Abstract
The contagious respiratory illness coronavirus disease 2019 (COVID-19) has had an unprecedented impact on both global health and society, causing a global pandemic due to its rapid transmission. The emergence of numerous variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underscores the critical importance of accurately diagnosing variants of concern (VOCs). Viruses have demonstrated a remarkable ability to evolve and adapt to their environments. Therefore, it is crucial to develop effective diagnostic methods that provide rapid, high sensitivity, and selectivity in a point-of-care (PoC) format, meeting the vital need for detecting and addressing emerging new viruses in the future. With the development of nanotechnology and biotechnology, there have been innovations in rapid, multiplexed, and portable sensors with high sensitivity and specificity. In this review, we discuss the fundamental properties of the SARS-CoV-2 virus, conventional diagnostic methods, and recent developments from the perspective of electrochemical- and nanophotonic-based SARS-CoV-2 biosensors, including our recent work.
Keywords
SURFACE-PLASMON RESONANCE; SELF-ASSEMBLED MONOLAYER; NUCLEIC-ACID DETECTION; SARS-COV; VIRUS; SPIKE; CLEAVAGE; PLATFORM; BINDING; FUSION; Nanophotonic biosensor; SARS-CoV-2; Electrochemical biosensor
ISSN
1976-0280
URI
https://pubs.kist.re.kr/handle/201004/149540
DOI
10.1007/s13206-024-00138-2
Appears in Collections:
KIST Article > 2024
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