Browsing byAuthorPae, Ae Nim
Showing results 1 to 120 of 214
| Issue Date | Title | Author(s) |
|---|---|---|
| 2019-10 | 3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA(A)-benzodiazepine Receptors | Woo, Junsung; Yang, Hyejin; Yoon, Minseok; Gadhe, Changdev G.; Pae, Ae Nim; Cho, Suengmok; Lee, C. Justin |
| 2007-01-15 | 3D pharmacophore based virtual screening of T-type calcium channel blockers | Doddareddy, Munikumar Reddy; Choo, Hyunah; Cho, Yong Seo; Rhim, Hyewhon; Koh, Hun Yeong; Lee, Jung-Ha; Jeong, Seong-Woo; Pae, Ae Nim |
| 2011-02 | 3D QSAR pharmacophore model based on diverse IKK beta inhibitors | Nagarajan, Shanthi; Ahmed, Asif; Choo, Hyunah; Cho, Yong Seo; Oh, Kwang-Seok; Lee, Byung Ho; Shin, Kye Jung; Pae, Ae Nim |
| 2008-10-03 | 5- and 6-exocyclic products, cis-2,3,5-trisubstituted tetrahydrofurans, and cis-2,3,6-trisubstituted tetrahydropyrans via Prins-type cyclization | Chavre, Satish N.; Choo, Hyunah; Lee, Jae Kyun; Pae, Ae Nim; Kim, Youseung; Cho, Yong Seo |
| 2006-08-03 | 5-Exocyclic products, 2,3,5-trisubstituted tetrahydrofurans via prins-type cyclization | Chavre, Satish N.; Choo, Hyunah; Cha, Joo Hwan; Pae, Ae Nim; Choi, Kyung Il; Cho, Yong Seo |
| 2012-01-01 | 5-HT2C receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs | Jang, Jae Wan; Baek, Je-sook; Choi, Gil Don; Park, Woo-Kyu; Cho, Yong Seo; Baek, Du-Jong; Pae, Ae Nim |
| 2012-02 | 9-[(E)-2-(2-Methoxyphenyl)ethenyl]-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8 -dione | Cha, Joo Hwan; Pae, Ae Nim; Lee, Jae Kyun; Cho, Yong Seo |
| 2019-10-29 | A beta modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism | Lee, Hae Nim; Sim, Kyoung Mi; Kim, Hyunbin; Ju, Jeongmin; Pae, Ae Nim; Park, Jae-Bong; Ryu, Hoon; Seong, Jihye |
| 2011-12-16 | A Concise Synthesis of Tetrabenazine: An Intramolecular Aza-Prins-Type Cyclization via Oxidative C-H Activation | Son, Young Wook; Kwon, Tae Hui; Lee, Jae Kyun; Pae, Ae Nim; Lee, Jae Yeol; Cho, Yong Seo; Min, Sun-Joon |
| 2020-01-01 | A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model | Kim, Hyeon Jeong; Jang, Bo Ko; Park, Jong-Hyun; Choi, Ji Won; Park, Sun Jun; Byeon, Seong Rim; Pae, Ae Nim; Lee, Yang Sup; Cheong, Eunji; Park, Ki Duk |
| 2018-07 | A Novel Phenylsulfonamide Ameliorates the Cognitive Impairment in Mice Induced by Scopolamine | Kim, Sun Young; Jung, Da Woon; Yoon, Hong Bin; Lee, Hwi-Ho; Lee, Jeong-Hun; Shin, Ji Sun; Lim, Dami; Kim, Hyoung Ja; Pae, Ae Nim; Park, Jeong Ho; Ryu, Jong Hoon; Lee, Kyung-Tae; Lee, Jae Yeol |
| 2018-07 | A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer | Fang, Zhenghuan; Han, Boreum; Jung, Kyung Hee; Lee, Ju-Hyeon; El-Damasy, Ashraf Kareem; Gadhe, Changdev G.; Kim, Soo Jung; Yan, Hong Hua; Park, Jung Hee; Lee, Ji Eun; Kang, Yeo Wool; Pae, Ae Nim; Keum, Gyochang; Hong, Soon-Sun |
| 2017-05 | A Potential PET Radiotracer for the 5-HT2C Receptor: Synthesis and in Vivo Evaluation of 4-(3-[F-18]fluorophenethoxy)pyrimidine | Kim, Juhyeon; Moon, Byung Seok; Lee, Byung Chul; Lee, Ho-Young; Kim, Hak-Joong; Choo, Hyunah; Pae, Ae Nim; Cho, Yong Seo; Min, Sun-Joon |
| 2015-05-15 | ABL kinase inhibitory and antiproliferative activity of novel picolinamide based benzothiazoles | El-Damasy, Ashraf Kareem; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Keum, Gyochang |
| 2016-11-01 | alpha-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Mice through GABA(A)-benzodiazepine Receptors | Yang, Hyejin; Woo, Junsung; Pae, Ae Nim; Um, Min Young; Cho, Nam-Chul; Park, Ki Duk; Yoon, Minseok; Kim, Jiyoung; Lee, C. Justin; Cho, Suengmok |
| - | An efficient synthesis of 2,7-disubstituted oxepane derivatives via Prins-type cyclization | Reddy Ullapu Punna; Min Sun Joon; Lee, Jae Kyun; Pae, Ae Nim; Kim, You Seung; Chang, Moon Ho; Cho, Yong Seo |
| 2015-09 | Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation | Park, Jong-Hyun; Choi, Ji Won; Ju, Eun Ji; Pae, Ae Nim; Park, Ki Duk |
| 2019-07 | Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator | Choi, Ji Won; Shin, Su Jeong; Kim, Hyeon Ji; Park, Jong-Hyun; Kim, Hyeon Jeong; Lee, Elijah Hwejin; Pae, Ae Nim; Bahn, Yong Sun; Park, Ki Duk |
| 2010-11-15 | Arylpiperazine-containing pyrimidine 4-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant | Kim, Jong Yup; Kim, Deukjoon; Kang, Suk Youn; Park, Woo-Kyu; Kim, Hyun Jung; Jung, Myung Eun; Son, Eun-Jung; Pae, Ae Nim; Kim, Jeongmin; Lee, Jinhwa |
| 2010-03-01 | Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant | Kang, Suk Youn; Park, Eun-Jung; Park, Woo-Kyu; Kim, Hyun Jung; Jeong, Daeyoung; Jung, Myung Eun; Song, Kwang-Seop; Lee, Suk Ho; Seo, Hee Jeong; Kim, Min Ju; Lee, MinWoo; Han, Ho-Kyun; Son, Eun-Jung; Pae, Ae Nim; Kim, Jeongmin; Lee, Jinhwa |
| 2011-06-20 | Binding Mode Prediction of 5-Hydroxytryptamine 2C Receptor Ligands by Homology Modeling and Molecular Docking Analysis | Ahmed, Asif; Nagarajan, Shanthi; Doddareddy, Munikumar Reddy; Cho, Yong Seo; Pae, Ae Nim |
| 2008-01-20 | Classification of piperazinylalkylisoxazole library by recursive partitioning | Kim, Hye-Jung; Park, Woo-Kyu; Cho, Yong Seo; No, Kyoung Tai; Koh, Hun Yeong; Choo, Hyunah; Pae, Ae Nim |
| - | Common feature hypothesis based virtual screening of 5-HT2C agonists using HipHop and HipHopRefine module of CATALYST | Pae, Ae Nim; Ahmed Asif; Choo, Hyunah; Cho, Yong Seo |
| 2007-05 | Comparative QSAR studies on peptide deformylase inhibitors | Lee, Ji Young; Doddareddy, Munikumar Reddy; Cho, Yong Seo; Choo, Hyunah; Koh, Hun Yeong; Kang, Jae-Hoon; No, Kyoung Tai; Pae, Ae Nim |
| 2011-01-15 | Computational approach to the identification of novel Aurora-A inhibitors | Morshed, Mohammad Neaz; Cho, Yong Seo; Seo, Seon Hee; Han, Ki-Cheol; Yang, Eun Gyeong; Pae, Ae Nim |
| 2020-01 | CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual | Yun, Yeomin; Hong, Sung-Ah; Kim, Ka-Kyung; Baek, Daye; Lee, Dongsu; ASHWINI MACHHINDRA LONDHE; Lee, Minhyung; Yu, Jihyeon; McEachin, Zachary T.; Bassell, Gary J.; Bowser, Robert; Hales, Chadwick M.; Cho, Sung-Rae; Kim, Janghwan; Pae, Ae Nim; Cheong, Eunji; Kim, Sangwoo; Boulis, Nicholas M.; Bae, Sangsu; Ha, Yoon |
| 2017-01 | Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agents | El-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Kim, Eunice Eunkyeong; Keum, Gyochang |
| 2016-06-10 | Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-Raf(V600E) and C-Raf kinase inhibitory activities | El-Damasy, Ashraf Kareem; Lee, Ju-Hyeon; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Keum, Gyochang |
| 2013-09-01 | Design and synthesis of novel series of 5-HT6 receptor ligands having indole, a central aromatic core and 1-amino-4 methyl piperazine as a positive ionizable group | Hayat, Faisal; Cho, Sungjin; Rhim, Hyewhon; Viswanath, Ambily Nath Indu; Pae, Ae Nim; Lee, Jae Yeol; Choo, Dong Joon; Choo, Hea-Young Park |
| - | Design, Synthesis and Biological Evaluation of Piperidine and Piperazine Derivatives as T-type Calcium Channel Blockers | Choi Yeon hee; Song Chi man; Min Sun Joon; Lee, Jae Kyun; Pae, Ae Nim; 백두종; Chang, Moon Ho; Cho, Yong Seo |
| 2007-01-15 | Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers | Kim, Hwa Sil; Kim, Yoonjee; Doddareddy, Munikumar Reddy; Seo, Seon Hee; Rhim, Hyewhon; Tae, Jinsung; Pae, Ae Nim; Choo, Hyunah; Cho, Yong Seo |
| 2017-06-15 | Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-beta-induced mPTP opening | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Paik, Sora; Do, Jimin; Park, Jong-Hyun; Park, Ki Duk; Moon, Bongjin; Park, Woo Kyu; Cho, Heeyeong; Jeong, Dae Young; Roh, Eun Joo |
| 2015-08 | Design, synthesis, in-vitro antiproliferative activity and kinase profile of new picolinamide based 2-amido and ureido quinoline derivatives | El-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Kim, Key-Sun; Keum, Gyochang |
| - | Determination of a 5HT2C Agonist, KOPC-20010 (KP10), in Rat Plasma and Urine by Gas-Chromatography/Mass Spectrometry and its Pharmacokinetics in Rats | Im Hye-yeon; Lakshmi; Haque; Yang Ha Yun; Pae, Ae Nim; Kim Chan-Hwa; Kwon, Oh-Seung |
| 2019-10 | Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent | Shin, Seulgi; Lim, Sungsu; Song, Ji Yeon; Kim, Dohee; Choi, Min Jeong; Gadhe, Changdev G.; Park, A. Young; Pae, Ae Nim; Kim, Yun Kyung |
| 2019-11 | Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy | Kim, Byung-Hak; Lee, Haeri; Song, Yeonghun; Park, Joon-Suk; Gadhe, Changdev G.; Choi, Jiwon; Lee, Chung-Gi; Pae, Ae Nim; Kim, Sanghee; Ye, Sang-Kyu |
| - | Development of Piperidine and Pyrrolidine Derivatives as Mitochondrial Function Modulators | Jung Sun hwa; 최기항; Lee, Jae Kyun; Pae, Ae Nim; Cho, Yong Seo; Min Sun-Joon |
| 2013-10 | Diastereoselective Synthesis of 2,6-Disubstituted 4-(Dimethoxymethyl)tetra-hydropyrans Using TMSOTf-Promoted Prins-Pinacol Cyclization | Kim, Young Seub; Lee, Jae Kyun; Pae, Ae Nim; Cho, Yong Seo; Min, Sun-Joon |
| 2017-11 | Direct interaction with 14-3-3 gamma promotes surface expression of Best1 channel in astrocyte | Oh, Soo-Jin; Woo, Junsung; Lee, Young-Sun; Cho, Minhee; Kim, Eunju; Cho, Nam chul; Park, Jae-Yong; Pae, Ae Nim; Lee, C. Justin; Hwang, Eun Mi |
| 2015-06-05 | Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain | Nam, Mina; Kim, TaeHun; Kwak, Jinsook; Seo, Seon Hee; Ko, Min Kyung; Lim, Eun Jeong; Min, Sun-Joon; Cho, Yong Seo; Keum, Gyochang; Baek, Du-Jong; Lee, Jiyoun; Pae, Ae Nim |
| 2013-08 | Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives | Kim, TaeHun; Keum, Gyochang; Pae, Ae Nim |
| 2017-03-10 | Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction | Elkamhawy, Ahmed; Park, Jung-Eun; Hassan, Ahmed H. E.; Ra, Hyunhwa; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Moon, Bongjin; Park, Hyun-Mee; Roh, Eun Joo |
| 2015-12-15 | Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR(2)) antagonists | Cho, Nam-Chul; Cha, Ji Hyoun; Kim, Hyojin; Kwak, Jinsook; Kim, Dohee; Seo, Seung-Hwan; Shin, Ji-Sun; Kim, TaeHun; Park, Ki Duk; Lee, Jiyoun; No, Kyoung Tai; Kim, Yun Kyung; Lee, Kyung-Tae; Pae, Ae Nim |
| 2021-11 | Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability and action | Elkamhawy, Ahmed; Kim, Hyeon Jeong; Elsherbeny, Mohamed H.; Paik, Sora; Park, Jong-Hyun; Gotina, Lizaveta; Abdellattif, Magda H.; Gouda, Noha A.; Cho, Jungsook; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2016-01-02 | Discovery of a broad spectrum antiproliferative agent with selectivity for DDR1 kinase: cell line-based assay, kinase panel, molecular docking, and toxicity studies | Elkamhawy, Ahmed; Park, Jung-eun; Cho, Nam-Chul; Sim, Taebo; Pae, Ae Nim; Roh, Eun Joo |
| 2016-08-05 | Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity | El-Damasy, Ashraf Kareem; Cho, Nam-Chul; Nam, Ghilsoo; Pae, Ae Nim; Keum, Gyochang |
| - | Discovery of a potential T-Type Calcium Channel blocker for the treatment of Neuropathic Pain | Abdul Waheed Ahmed; Song Chi man; Min Sun Joon; Lee, Jae Kyun; Pae, Ae Nim; Chang, Moon Ho; Cho, Yong Seo |
| 2017-01-05 | Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease | Kim, TaeHun; Yang, Ha Yun; Park, Beoung Gun; Jung, Seo Yun; Park, Jong-Hyun; Park, Ki Duk; Min, Sun-Joon; Tae, Jinsung; Yang, Hyejin; Cho, Suengmok; Cho, Sung Jin; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun; Pae, Ae Nim |
| 2020-01 | Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B | Elkamhawy, Ahmed; Paik, Sora; Kim, Hyeon Jeong; Park, Jong-Hyun; Londhe, Ashwini M.; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2017-10 | Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in A beta-induced mitochondrial dysfunction | Park, Insun; Londhe, Ashwini M.; Lim, Ji Woong; Park, Beoung-Geon; Jung, Seo Yun; Lee, Jae Yeol; Lim, Sang Min; No, Kyoung Tai; Lee, Jiyoun; Pae, Ae Nim |
| 2015-08-16 | Discovery of novel 18 kDa tranlocator (TSPO) ligands for the treatment of Alzheimer's disease | Kim, TaeHun; Park, Beoung-Geon; Pae, Ae Nim; Jung, Seo Yun; Lee, Jiyoun; Neaz, Mohammad |
| 2011-05-15 | Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors | Kim, Sora; Jung, Jin Kyo; Lee, Hyo Seon; Kim, Youngjae; Kim, Jiyoon; Choi, Kihang; Baek, Du-Jong; Moon, Bongjin; Oh, Kwang-Seok; Lee, Byung Ho; Shin, Kye Jung; Pae, Ae Nim; Nam, Ghilsoo; Roh, Eun Joo; Cho, Yong Seo; Choo, Hyunah |
| 2015-10-20 | Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM) | Elkamhawy, Ahmed; Viswanath, Ambily Nath Indu; Pae, Ae Nim; Kim, Hyeon Young; Heo, Jin-Chul; Park, Woo-Kyu; Lee, Chong-Ock; Yang, Heekyoung; Kim, Kang Ho; Nam, Do-Hyun; Seol, Ho Jun; Cho, Heeyeong; Roh, Eun Joo |
| 2017-08-20 | Discovery of potent antiallodynic agents for neuropathic pain targeting P2X3 receptors | Jung, Young-Hwan; Kim, Yeo Ok; Lin, Hai; Cho, Joong-Heui; Park, Jin-Hee; Lee, So-Deok; Kim, Yong-Chul; Kang, Koon Mook; Kim, Yoon-Gyoon; Pae, Ae Nim; Ko, Hyojin; Park, Chul-Seung; Yoon, Myung Ha; Bae, Jinsu |
| 2017-07 | Discovery of Potent Antiallodynic Agents for Neuropathic Pain Targeting P2X3 Receptors | Jung, Young-Hwan; Kim, Yeo Ok; Lin, Hai; Cho, Joong-Heui; Park, Jin-Hee; Lee, So-Deok; Bae, Jinsu; Kang, Koon Mook; Kim, Moon-Gyoon; Pae, Ae Nim; Ko, Hyojin; Park, Chul-Seung; Yoon, Myung Ha; Kim, Yong-Chul |
| - | Discovery of Selective and Potential T-type Calcium Channel Modulators: Synthesis and Biological Evaluation of Piperazine Analogues | Shin Sun-mi; Pae, Ae Nim; Lee, Jae Kyun; 한소엽; Min Sun-Joon; Cho, Yong Seo |
| 2017-12-01 | Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against A beta-induced neurotoxicity | Kim, TaeHun; Son, Woo Seung; Morshed, Mohammad Neaz; Londhe, Ashwini M.; Jung, Seo Yun; Park, Jong-Hyun; Park, Woo-Kyu; Lim, Sang Min; Park, Ki Duk; Cho, Sung Jin; Jeong, Kyu-Sung; Lee, Jiyoun; Pae, Ae Nim |
| 2012-02 | (E)-9-(4-Chlorostyryl)-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione | Lee, Jae Kyun; Pae, Ae Nim; Cho, Yong Seo; Cha, Joo Hwan |
| 2014-08-14 | Efficient synthesis of mibefradil analogues: an insight into in vitro stability | Lee, Ji Eun; Kwon, Tae Hui; Gu, Su Jin; Lee, Duck-Hyung; Kim, B. Moon; Lee, Jae Yeol; Lee, Jae Kyun; Seo, Seon Hee; Pae, Ae Nim; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon |
| 2013-05 | Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca2+ signaling in Huntington's disease | Lee, Junghee; Hwang, Yu Jin; Shin, Jong-Yeon; Lee, Won-Chul; Wie, Jinhong; Kim, Ki Yoon; Lee, Min Young; Hwang, Daehee; Ratan, Rajiv R.; Pae, Ae Nim; Kowall, Neil W.; So, Insuk; Kim, Jong-Il; Ryu, Hoon |
| 2020-02-15 | Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT2A, 5-HT2C, and the serotonin transporter | Kim, Jihye; Cha, Eunji; Park, Woo Kyu; Lee, Hye Yeon; Lim, Sang Min; Kim, Hak Joong; Pae, Ae Nim |
| 2023-08 | Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis | Cha, Eunji; Kim, Jushin; Gotina, Lizaveta; Kim, Jaehwan; Kim, Hyeon Jeong; Seo, Seon Hee; Park, Jeong-Eun; Joo, Jeongmin; Kang, Minsik; Lee, Jaeick; Hwang, Hayoung; Kim, Hak Joong; Pae, Ae Nim; Park, Ki Duk; Park, Jong-Hyun; Lim, Sang Min |
| 2014-12 | Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers | Jung, Sun Hwa; Choi, Kihang; Pae, Ae Nim; Lee, Jae Kyun; Choo, Hyunah; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon |
| 2011-01 | Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers | Choi, Yeon-hee; Baek, Du Jong; Seo, Seon Hee; Lee, Jae Kyun; Pae, Ae Nim; Cho, Yong Seo; Min, Sun-Joon |
| - | Flexible docking study for searching active ligands as GSK 3b Inhibitors | Yeon Joo Lee; Cho, Yong Seo; Pae, Ae Nim; Chang, Moon Ho; Koh, Hun Yeong |
| 2008-05 | Functional human 5-HT6 receptor assay for high throughput screening of chemical ligands and binding proteins | Kim, Hyun-Ji; Yun, Hyung-Mun; Kim, Taehyun; Nam, Ghilsoo; Roh, Eun Joo; Kostenis, Evi; Choo, Hea-Young Park; Pae, Ae Nim; Rhim, Hyewhon |
| 2010-08-15 | Further optimization of novel pyrrole 3-carboxamides for targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant | Kang, Suk Youn; Park, Eun-Jung; Park, Woo-Kyu; Kim, Hyun Jung; Choi, Gildon; Jung, Myung Eun; Seo, Hee Jeong; Kim, Min Ju; Pae, Ae Nim; Kim, Jeongmin; Lee, Jinhwa |
| 2019-06 | Gait Ignition Failure in JNPL3 Human Tau-mutant Mice | Jang, HoChung; Ryu, Jung Hwa; Shin, Kyung Mm; Seo, Na-young; Kim, Gyu Hyun; Huh, Yang Hoon; Pae, Ae Nim; Lee, Kea Joo |
| 2022-10 | Glutamate Permeability of Chicken Best1 | Lee, Jung Moo; Gadhe Changdev Gorakshnath; Kang, Hyunji; Pae, Ae Nim; Lee, ChangJoon Justin |
| 2018-08 | GRP78-targeted in-silico virtual screening of novel anticancer agents | Viswanath, Ambily Nath Indu; Lim, Ji Woong; Seo, Seon Hee; Lee, Jae Yeol; Lim, Sang Min; Pae, Ae Nim |
| 2024-09 | Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease | Kim, Hyeon Jeong; Kim, Haelee; Song, Jaeyoung; Hong, Jun Young; Lee, Elijah Hwejin; Londhe, Ashwini M; Choi, Ji Won; Park, Sun Jun; Oh, Eunseok; Yoon, Heeseok; Hwang, Hoosang; Hahn, Dongyup; Jung, Kyungjin; Kwon, Sugyeong; Kadayat, Tara Man; Ma, Min Jung; Joo, Jeongmin; Kim, Jina; Bae, Jae Hyun; Hwang, Hayoung; Pae, Ae Nim; Cho, Sung Jin; Park, Jong Hyun; Chin, Jungwook; Kang, Heonjoong; Park, Ki Duk |
| 2012-06-01 | Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol | Cho, Suengmok; Park, Ji-Hae; Pae, Ae Nim; Han, Daeseok; Kim, Dongsoo; Cho, Nam-Chul; No, Kyoung Tai; Yang, Hyejin; Yoon, Minseok; Lee, Changho; Shimizu, Makoto; Baek, Nam-In |
| 2018-09-05 | Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease | Lim, Ji Woong; Kim, Seok Kyu; Choi, Seo Yun; Kim, Dong Hoi; Gadhe, Changdev G.; Lee, Hae Nim; Kim, Hyo-Ji; Kim, Jina; Cho, Sung Jin; Hwang, Hayoung; Seong, Jihye; Jeong, Kyu-Sung; Lee, Jae Yeol; Lim, Sang Min; Lee, Jae Wook; Pae, Ae Nim |
| 2010-09-15 | Identification of novel antitubercular compounds through hybrid virtual screening approach | Muddassar, Muhammad; Jang, Jae Wan; Hong, Seung Gon; Cho, Yong Seo; Kim, Eunice Eunkyung; Keum, Kyo Chang; Oh, Taegwon; Cho, Sang-Nae; Pae, Ae Nim |
| 2022-03 | Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM-GBSA approaches | Nada, Hossam; Lee, Kyeong; Gotina, Lizaveta; Pae, Ae Nim; Elkamhawy, Ahmed |
| 2009-07-01 | Identification of novel serotonin 2C receptor ligands by sequential virtual screening | Ahmed, Asif; Choo, Hyunah; Cho, Yong Seo; Park, Woo-Kyu; Pae, Ae Nim |
| 2017-09 | Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators | Kim, Juhyeon; Jo, Hanbyeol; Lee, Hyunseung; Choo, Hyunah; Kim, Hak Joong; Pae, Ae Nim; Cho, Yong Seo; Min, Sun-Joon |
| 2012-09 | Identification of structural determinants of ligand selectivity in 5-HT2 receptor subtypes on the basis of protein-ligand interactions | Jang, Jae Wan; Kim, Min Sup; Cho, Yong Seo; Cho, Art E.; Pae, Ae Nim |
| 2016-12 | Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently | Viswanath, Ambily Nath Indu; Jung, Seo Yun; Hwang, Eun Mi; Park, Ki Duk; Lim, Sang Min; Min, Sun-Joon; Cho, Yong Seo; Pae, Ae Nim |
| 2010-10-15 | IKK beta inhibitor identification: a multi-filter driven novel scaffold | Nagarajan, Shanthi; Choo, Hyunah; Cho, Yong Seo; Shin, Kye Jung; Oh, Kwang-Seok; Lee, Byung Ho; Pae, Ae Nim |
| 2009-04-01 | IKK beta inhibitors identification part I: Homology model assisted structure based virtual screening | Nagarajan, Shanthi; Doddareddy, Munikumar Reddy; Choo, Hyunah; Cho, Yong Seo; Oh, Kwang-Seok; Lee, Byung Ho; Pae, Ae Nim |
| 2010-06-01 | IKK beta inhibitors identification part II: Ligand and structure-based virtual screening | Nagarajan, Shanthi; Choo, Hyunah; Cho, Yong Seo; Oh, Kwang-Seok; Lee, Byung Ho; Shin, Kye Jung; Pae, Ae Nim |
| - | IKKβ inhibitor identification: a novel multi-filter driven scaffold | Nagarajan Shanthi; Choo, Hyunah; Cho, Yong Seo; Kwang-Seok Oh; Byung Ho Lee; Pae, Ae Nim |
| 2016-01 | Immunomodulatory Activities of the Benzoxathiole Derivative BOT-4-One Ameliorate Pathogenic Skin Inflammation in Mice | Lee, Hyun Gyu; Cho, Nam-chul; Jeong, Ae Jin; Li, Yu-Chen; Rhie, Sung-Ja; Choi, Jung Sook; Lee, Kwang-Ho; Kim, Youngsoo; Kim, Yong-Nyun; Kim, Myoung-Hwan; Pae, Ae Nim; Ye, Sang-Kyu; Kim, Byung-Hak |
| - | Improvement of pharmacological profile of mibefradil, a selective T-type calcium channel blocker: Synthesis and biological evaluation of dihydrobenzofuran analogues derived from mibefradil | Shin Sun-mi; Ku Su Jin; Min Sun-Joon; 한소엽; Pae, Ae Nim; Lee, Jae Kyun; Cho, Yong Seo |
| 2011-01-20 | In silico Analysis on hERG Channel Blocking Effect of a Series of T-type Calcium Channel Blockers | Jang, Jae Wan; Song, Chi Man; Choi, Kee Hyun; Cho, Yong Seo; Baek, Du-Jong; Shin, Kye Jung; Pae, Ae Nim |
| 2017-10 | In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level | Park, Insun; Hwang, Yu Jin; Kim, TaeHun; Viswanath, Ambily Nath Indu; Londhe, Ashwini M.; Jung, Seo Yun; Sim, Kyoung Mi; Min, Sun-Joon; Lee, Ji Eun; Seong, Jihye; Kim, Yun Kyung; No, Kyoung Tai; Ryu, Hoon; Pae, Ae Nim |
| 2006-05 | In silico renal clearance model using classical Volsurf approach | Doddareddy, Munikumar R.; Cho, Yong Seo; Koh, Hun Yeong; Kim, Dong Hyun; Pae, Ae Nim |
| 2017-12 | In silico-designed novel non-peptidic ABAD L-D hot spot mimetics reverse A-induced mitochondrial impairments in vitro | Viswanath, Ambily Nath Indu; Kim, TaeHun; Jung, Seo Yun; Lim, Sang Min; Pae, Ae Nim |
| 2001-09 | Indium-mediated allylation reactions of α-chlorocarbonyl compounds and preparation of allylic epoxides | Shin, Jeong Ah; Choi, Kyung Il; Pae, Ae Nim; Koh, Hun Yeong; Kang, H.-Y.; Cho, Yong Seo |
| - | Intermolecular Double Prins-type Cyclization | Reddy Ullapu Punna; Satish N. Chavre; Min Sun Joon; Lee, Jae Kyun; Choo, Hyunah; Pae, Ae Nim; Chang, Moon Ho; Kim, You Seung; Cho, Yong Seo |
| 2009-03 | Intermolecular Double Prins-Type Cyclization: A Facile and Efficient Synthesis of 1,6-Dioxecanes | Ullapu, Punna Reddy; Min, Sun-Joon; Chavre, Satish N.; Choo, Hyunah; Lee, Jae Kyun; Pae, Ae Nim; Kim, Youseung; Chang, Moon Ho; Cho, Yong Seo |
| 2019-11 | Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques | Londhe, Ashwini Machhindra; Gadhe, Changdev Gorakshnath; Lim, Sang Min; Pae, Ae Nim |
| 2016-07 | Isoxazoline, Isoxazole, and Oxadiazole Derivatives as M-1 Muscarinic Acetylcholine Receptor Agonists | Muthusamy, Selvaraj; Lee, Soo Min; Huang, Minghua; Cho, Nam-Chul; Nam, Ghilsoo; Pae, Ae Nim; Rhim, Hyewhon; Keum, Gyochang; Choi, Kyung Il |
| 2010-12 | KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models | Lee, Min Ju; Shin, Teo Jeon; Lee, Jie Eun; Choo, Hyunah; Koh, Hun Yeong; Chung, Hye Jin; Pae, Ae Nim; Lee, Sang Chul; Kim, Hyun Jeong |
| 2007-02-01 | Lead discovery and optimization of T-type calcium channel blockers | Park, Jung Hwan; Choi, Jin Kyu; Lee, Eunjung; Lee, Jae Kyun; Rhim, Hyewhon; Seo, Seon Hee; Kim, Yoonjee; Doddareddy, Munikumar Reddy; Pae, Ae Nim; Kang, Jahyo; Roh, Eun Joo |
| 2023-03 | Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in TauP301L-BiFC mice | Lim, Sung su; Shin, Seul gi; Sung, Yoonsik; Lee, Haeun; Kim, Kyu Hyeon; 송지연; Lee, Gwan Ho; Aziz, Hira; 나탈리아 루키안에넨코; Kang Dong Min; 니콜렛 보에센; Hyeanjeong Jeong; ABDILDINOVA AIZHAN; Junghee Lee; Yu, Byung Yong; LIM, SANG MIN; Jun-Seok Lee; Ryu, Hoon; Pae, Ae Nim; Kim, Yun Kyung |
| 2014-07 | Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABA(A) receptor | Cho, Suengmok; Yoon, Minseok; Pae, Ae Nim; Jin, Young-Ho; Cho, Nam-Chul; Takata, Yohko; Urade, Yoshihiro; Kim, Sojin; Kim, Jin-Soo; Yang, Hyejin; Kim, Jiyoung; Kim, Jinkyoung; Han, Jin-Kyu; Shimizu, Makoto; Huang, Zhi-Li |
| 2025-01 | Mice deficient in TWIK-1 are more susceptible to kainic acid-induced seizures | Kim, Ajung; Bae, Yeonju; Gadhe, Changdev G.; Jung, Hyun-Gug; Yang, Esther; Kim, Hyun; Lee, Jaekwang; Shim, Chanseob; Sung, Young Hoon; Noh, Junyeol; Kim, Eun-Jin; Kang, Dawon; Pae, Ae Nim; Hwang, Eun Mi; Park, Jae-Yong |
| 2020-01-31 | Mitochondrial dysfunction and Alzheimer's disease: prospects for therapeutic intervention | Lim, Ji Woong; Lee, Jiyoun; Pae, Ae Nim |
| 2021-01 | Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model | Hwang, Yu Jin; Hyeon, Seung Jae; Kim, Younghee; Lim, Sungsu; Lee, Min Young; Kim, Jieun; ASHWINI, MACHHINDRA LONDHE; Gotina, Lizaveta; Kim, Yunha; Pae, Ae Nim; Cho, Yong Seo; Seong, Jihye; Seo, Hyemyung; Kim, Yun Kyung; Choo, Hyunah; Ryu, Hoon; Min, Sun-Joon |
| 2020-11 | Molecular Characterization of Hepatitis C Virus for Developed Antiviral Agents Resistance Mutations and New Insights into in-silico Prediction Studies | Adel El-Sokkary, Mohamed M.; Gotina, Lizaveta; Al-Sanea, Mohammad M.; Pae, Ae Nim; Elbargisy, Rehab Mohammed |
| 2006-09-04 | N-Acyliminium ion cyclizations of trimethylsilylmethylallenes | Kim, Sang Hee; Kim, Hyung Gyu; Choo, Hyunah; Cha, Joo Hwan; Pae, Ae Nim; Koh, Hun Yeong; Chung, Bong Young; Cho, Yong Seo |
| 2024-01 | NeuM: A Neuron-Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin-Mediated Endocytosis in Primary Neurons | Yoonk Sik Sung; Gotina, Lizaveta; Kim, Kyu Hyeon; Lee, Jung Yeol; Seulgi Shin; Aziz, Hira; Kang, Dong Min; Liu, Xiao; Hong, Na-Kyeong; Lee, Hong-Guen; Lee, Jun-Seok; Ku, Hyeyeong; Jeong, Cherl hyun; Pae, Ae Nim; Lim, Sungsu; Chang, Young-Tae; Kim, Yun Kyung |
| 2023-02 | Neuroprotective Effects of Ethanol Extract of Polyscias fruticosa (EEPF) against Glutamate-Mediated Neuronal Toxicity in HT22 Cells | Selvaraj, Baskar; Le, Tam Thi; Kim, Dae Won; Jung, Bo Hyun; Yoo, Ki-Yeon; Ahn, Hong Ryul; Thuong, Phuong Thien; Tran, Thi Thu Thuy; Pae, Ae Nim; Jung, Sang Hoon; Lee, Jae Wook |
| 2008-01 | New serotonin 5-HT6 ligands from common feature pharmacophore hypotheses | Kim, Hye-Jung; Doddareddy, Munikurnar Reddy; Choo, Hyunah; Cho, Yong Seo; No, Kyoung Tai; Park, Woo-Kyu; Pae, Ae Nim |
| 2019-03 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease | Park, Jong-Hyun; Ju, Yeon Ha; Choi, Ji Won; Song, Hyo Jung; Jang, Bo Ko; Woo, Junsung; Chun, Heejung; Kim, Hyeon Jeong; Shin, Su Jeong; Yarishkin, Oleg; Jo, Seonmi; Park, Mijeong; Yeon, Seul Ki; Kim, Siwon; Kim, Jeongyeon; Nam, Min-Ho; Londhe, Ashwini M.; Kim, Jina; Cho, Sung Jin; Cho, Suengmok; Lee, Changho; Hwang, Sung Yeoun; Kim, Sang Wook; Oh, Soo-Jin; Cho, Jeiwon; Pae, Ae Nim; Lee, C. Justin; Park, Ki Duk |
| 2018-11-15 | Novel 5,6-disubstituted pyrrolo[2,3-d]pyrimidine derivatives as broad spectrum antiproliferative agents: Synthesis, cell based assays, kinase profile and molecular docking study | Lee, Ju-Hyeon; El-Damasy, Ashraf K.; Seo, Seon Hee; Gadhe, Changdev G.; Pae, Ae Nim; Jeong, Nakcheol; Hong, Soon-Sun; Keum, Gyochang |
| 2016-07-15 | Novel 5-substituted-2-anilinoquinolines with 3-(morpholino or 4-methylpiperazin-1-yl)propoxy moiety as broad spectrum antiproliferative agents: Synthesis, cell based assays and kinase screening | El-Damasy, Ashraf Kareem; Cho, Nam-Chul; Pae, Ae Nim; Kim, Eunice Eunkyeong; Keum, Gyochang |
| 2010-03-01 | Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents | Devegowda, Vani N.; Kim, Jung Hyun; Han, Ki-Cheol; Yang, Eun Gyeong; Choo, Hyunah; Pae, Ae Nim; Nam, Ghilsoo; Choi, Kyung Il |
| 2008-01-15 | Novel GSK-3 beta inhibitors from sequential virtual screening | Kim, Hye-Jung; Choo, Hyunah; Cho, Yong Seo; No, Kyoung Tal; Pae, Ae Nim |
| - | Novel IKKβ Inhibitors Identification: Ligand and Structure-based virtual screening | Nagarajan Shanthi; Choo, Hyunah; Cho, Yong Seo; Shin, Kye Jung; Pae, Ae Nim |
| 2017-12-01 | Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders | Farag, Ahmed Karam; Elkamhawy, Ahmed; Londhe, Ashwini M.; Lee, Kyung-Tae; Pae, Ae Nim; Roh, Eun Joo |
| 2023-09 | Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants | Lee, Elliot H.; Park, Jung-eun; Gotina, Lizaveta; Han, Young-Eun; Viswanath, Ambily Nath Indu; Yoo, Seonguk; Moon, Bongjin; Hwang, Jin-Young; Park, Woo Kyu; Cho, Yoonjeong; Song, Chiman; Min, Sun-Joon; Hwang, Eun Mi; Lee, Hyunbeom; Pae, Ae Nim; Roh, Eun Joo; Oh, Soo-Jin |
| - | Novel Pyrazolopyrimidinone Derivatives as GSK-3β Inhibitors: Rational Design, an efficient Synthetic Route and Biological Evaluation. | Vani Nelamane; NAM, GHILSOO; Pae, Ae Nim; Kim Jung Hyun; Choi, Kyung Il |
| 2013-05 | Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity | Yang, Ha Yun; Tae, Jinsung; Seo, Yong Wan; Kim, Yoon Jung; Im, Hye Yeon; Choi, Gil Don; Cho, Heeyeong; Park, Woo-Kyu; Kwon, Oh Seung; Cho, Yong Seo; Ko, Minkyung; Jang, HyunSeo; Lee, Jaeick; Choi, Kihang; Kim, Chan-Hwa; Lee, Jiyoun; Pae, Ae Nim |
| 2014-09-12 | Novel quinazoline-urea analogues as modulators for A beta-induced mitochondrial dysfunction: Design, synthesis, and molecular docking study | Elkamhawy, Ahmed; Lee, Jiyoun; Park, Beoung-Geon; Park, Insun; Pae, Ae Nim; Roh, Eun Joo |
| 2008-03-01 | Novel quinazolinone derivatives as 5-HT7 receptor ligands | Na, Yong Ho; Hong, Sung Ho; Lee, Jung Hyang; Park, Woo-Kyu; Baek, Du-Jong; Koh, Hun Yeong; Cho, Yong Seo; Choo, Hyunah; Pae, Ae Nim |
| 2016-02 | Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach | Jang, Jae Wan; Cho, Nam-Chul; Min, Sun-Joon; Cho, Yong Seo; Park, Ki Duk; Seo, Seon Hee; No, Kyoung Tai; Pae, Ae Nim |
| 2007-01-01 | Novel T-type calcium channel blockers: Dioxoquinazoline carboxamide derivatives | Jo, Mi Na; Seo, Hee Jeong; Kim, Yoonji; Seo, n Hee Seo; Rhim, Hyewhon; Cho, Yong Seo; Cha, Joo Hwan; Koh, Hun Yeong; Choo, Hyunah; Pae, Ae Nim |
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