Structure-Property Relationships of 3D-Printable Chain-Extended Block Copolymers with Tunable Elasticity and Biodegradability

Authors
Kim, Ryung IlGEONCHANG LEELee, Jung-HyunPark, Ji JongLee, Albert S.Hwang, Seung Sang
Issue Date
2021-09
Publisher
AMER CHEMICAL SOC
Citation
ACS APPLIED POLYMER MATERIALS, v.3, no.9, pp.4708 - 4716
Abstract
Elastomeric bioscaffolds with tunable elasticity and biodegradability were synthesized via ring opening polymerization of polycaprolactone (PCL) and polylactide (PLA) with a bifunctional polyethylene glycol macroinitiator, followed by chain extension with diisocyanate to form urethane linkages. Through fine tuning of the macroinitiator and PCL/PLA weight fraction and molecular weight, a data set of elastomeric bioscaffolds gives structure-property insights into their thermal, mechanical, and biodegradability properties as they relate to triblock copolymer composition and mechanical weight. These materials were targeted to be 3D-printed by commercial devices, and their unique rheological properties enable impeccable multiscale microstructure formation. Simplicity in synthesis and fabrication as well as tunable biodegradability (1 day to 2 months) and elasticity (modulus 32-94 MPa) suggest the vast wide-ranging utility and prospective application in bioscaffolds for future therapeutic treatments.
Keywords
CRYSTALLIZATION BEHAVIOR; POLYCAPROLACTONE; POLYMERS; DEGRADATION; BLENDS; PCL; COMPOSITE; SCAFFOLDS; BIOINK; PLA; biodegradable polymers; bioelastomer; 3D printing; block copolymer; polyurethane
ISSN
2637-6105
URI
https://pubs.kist.re.kr/handle/201004/116507
DOI
10.1021/acsapm.1c00860
Appears in Collections:
KIST Article > 2021
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE