Application of polysaccharides for surface modification of nanomedicines
- Authors
- Doh, K.-O.; Yeo, Y.
- Issue Date
- 2012-12
- Citation
- Therapeutic Delivery, v.3, no.12, pp.1447 - 1456
- Abstract
- Polysaccharides have been used in various biomedical applications due to availability and biocompatibility. In particular, polysaccharides have gained increasing interest in the development of functional nanomedicines as a component to provide a stealth function, improve interactions with target tissues or enable environment-responsive drug release. This review discusses recent advances in nanomedicine engineering based on polysaccharides with a specific emphasis on the rationale, applications and the remaining challenges. ？ 2012 Future Science Ltd.
- Keywords
- chitosan; chondroitin sulfate; dextran; doxorubicin; heparin; hyaluronic acid; hydrophilic glycol chitosan; low molecular weight chitosan; nanoparticle; poly(alkylacyanoacrylate) nanoparticle; polyethyleneimine; polyglactin; polysaccharide; small interfering RNA; unclassified drug; bioaccumulation; cell interaction; cell transport; chemical modification; complex formation; conjugation; drug conformation; drug delivery system; drug dosage form comparison; endocytosis; gene silencing; genetic transfection; human; material coating; molecular dynamics; molecular weight; nanomedicine; nonhuman; particle size; priority journal; review; structure activity relation; surface modification; Chitosan; Chondroitin Sulfates; Heparin; Humans; Hyaluronic Acid; Nanomedicine; Nanoparticles; Polysaccharides; Surface Properties; chitosan; chondroitin sulfate; dextran; doxorubicin; heparin; hyaluronic acid; hydrophilic glycol chitosan; low molecular weight chitosan; nanoparticle; poly(alkylacyanoacrylate) nanoparticle; polyethyleneimine; polyglactin; polysaccharide; small interfering RNA; unclassified drug; bioaccumulation; cell interaction; cell transport; chemical modification; complex formation; conjugation; drug conformation; drug delivery system; drug dosage form comparison; endocytosis; gene silencing; genetic transfection; human; material coating; molecular dynamics; molecular weight; nanomedicine; nonhuman; particle size; priority journal; review; structure activity relation; surface modification; Chitosan; Chondroitin Sulfates; Heparin; Humans; Hyaluronic Acid; Nanomedicine; Nanoparticles; Polysaccharides; Surface Properties
- ISSN
- 2041-5990
- Appears in Collections:
- KIST Article > 2012
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