DSpace at KISTKIST Article2010

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dc.contributor.authorMoon, Byung Seok-
dc.contributor.authorJo, Nam Hyun-
dc.contributor.authorLee, Kyo Chul-
dc.contributor.authorEi-Gamal, Mohammed I.-
dc.contributor.authorAn, Gwang Il-
dc.contributor.authorHong, Su Hee-
dc.contributor.authorChoi, Tae Hyun-
dc.contributor.authorChoi, Won-Kyoung-
dc.contributor.authorPark, Jin-Hun-
dc.contributor.authorCho, Jung-Hyuck-
dc.contributor.authorCheon, Gi Jeong-
dc.contributor.authorOh, Chang-Hyun-
dc.date.accessioned2024-01-20T18:04:17Z-
dc.date.available2024-01-20T18:04:17Z-
dc.date.created2022-01-10-
dc.date.issued2010-11-20-
dc.identifier.issn0253-2964-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/130911-
dc.description.abstractD-[(18) F]FMAU and L-[F-18]FMAU are F-18 labeled nucleoside analogue which have been efficiently synthesized in order to be a PET imaging probe D-[F-18]FMAU and L-[F-18]FMAU were compared as PET imaging agents using HSV1-TK gene expressing tumor-bearing mice Their cellular uptake profiles were also compared using MCA and MCA-TK cell lines D-[F-18]FMAU demonstrated higher cellular uptake and higher accumulation in MCA-TK tumor regions than L-[F-18]FMAU On the other hand, L-[F-18]FMAU showed higher MCA-TK/MCA ratio of %ID/g than that of D-[F-18]FMAU L-[F-18]FMAU can be utilized as a good candidate for HSV1-TK PET imaging It can be used for antiviral drug evaluation-
dc.languageEnglish-
dc.publisherKOREAN CHEMICAL SOC-
dc.subjectVIRUS THYMIDINE KINASE-
dc.subjectIN-VIVO-
dc.subjectDNA-SYNTHESIS-
dc.subjectFIALURIDINE-
dc.subjectCARCINOMA-
dc.subjectTHERAPY-
dc.subjectFIAU-
dc.titleComparison of D-[F-18]FMAU and L-[F-18]FMAU as PET Imaging Agents for HSV1-TK Gene Expression-
dc.typeArticle-
dc.identifier.doi10.5012/bkcs.2010.31.11.3309-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.31, no.11, pp.3309 - 3312-
dc.citation.titleBULLETIN OF THE KOREAN CHEMICAL SOCIETY-
dc.citation.volume31-
dc.citation.number11-
dc.citation.startPage3309-
dc.citation.endPage3312-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.identifier.kciidART001526263-
dc.identifier.wosid000284794100047-
dc.identifier.scopusid2-s2.0-78549282060-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusVIRUS THYMIDINE KINASE-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusDNA-SYNTHESIS-
dc.subject.keywordPlusFIALURIDINE-
dc.subject.keywordPlusCARCINOMA-
dc.subject.keywordPlusTHERAPY-
dc.subject.keywordPlusFIAU-
dc.subject.keywordAuthorHSV1-TK-
dc.subject.keywordAuthorD-[F-18]FMAU-
dc.subject.keywordAuthorL-[F-18]FMAU-
dc.subject.keywordAuthorPET imaging-
dc.subject.keywordAuthorMicroPET-
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KIST Article > 2010
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