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Synthesis and antibacterial activity of new 9-O-arylpropenyloxime ketolides

Authors
Nam, Ghilsoo; Kim, Yang Soo; Choi, Kyung Il
Issue Date
2010-04-15
Publisher
Pergamon Press Ltd.
Citation
Bioorganic & Medicinal Chemistry Letters, v.20, no.8, pp.2671 - 2674
Abstract
A novel series of 9-O-arylpropenyloxime ketolide was synthesized and evaluated for their antibacterial activity. This series of ketolide exhibited potent activity against clinically isolated gram-positive strains including Staphylococcus pneumoniae and Straptococcus Pyogenes. (C) 2010 Published by Elsevier Ltd.
Keywords
STREPTOCOCCUS-PNEUMONIAE; TELITHROMYCIN; SUSCEPTIBILITY; DERIVATIVES; RESISTANT; STREPTOCOCCUS-PNEUMONIAE; TELITHROMYCIN; SUSCEPTIBILITY; DERIVATIVES; RESISTANT; Ketolides; Macrolide antibiotics; 9-O-Arylpropenyloximes; Antibacterial activity
ISSN
0960-894X
URI
https://pubs.kist.re.kr/handle/201004/131540
DOI
10.1016/j.bmcl.2010.01.153
Appears in Collections:
KIST Article > 2010
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