Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Lee, JS | - |
dc.contributor.author | Kim, HJ | - |
dc.contributor.author | Lee, YS | - |
dc.date.accessioned | 2024-01-21T08:12:02Z | - |
dc.date.available | 2024-01-21T08:12:02Z | - |
dc.date.created | 2022-01-11 | - |
dc.date.issued | 2003-09 | - |
dc.identifier.issn | 0032-0943 | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/138248 | - |
dc.description.abstract | A new flavonoid glucuronide, apigenin 7-O-beta-D-(4'-caffeoyl)glucuronide (1), and the known compound, apigenin 7-O-beta-D-glucuronide, were isolated from the flowers of Chrysanthemum morifolium, along with five known flavonoids. The structure of 1 was elucidated by the aid of spectroscopic analyses. Among isolated compounds, apigenin 7-O-beta-D-(4"-caffeoyl)glucuronide showed strong HIV-1 integrase inhibitory activity (IC50 = 7.2 +/- 3.4 mug/ml) and anti-HIV activity in a cell culture assay (EC50 = 41.86 +/- 1.43 mug/ml) using H-IIIB infected MT-4 cells. | - |
dc.language | English | - |
dc.publisher | GEORG THIEME VERLAG KG | - |
dc.subject | IMMUNODEFICIENCY-VIRUS TYPE-1 | - |
dc.subject | C-13 NMR | - |
dc.subject | INTEGRASE | - |
dc.subject | GLYCOSIDES | - |
dc.subject | DERIVATIVES | - |
dc.subject | INHIBITORS | - |
dc.subject | MORIFOLIUM | - |
dc.subject | FLOWERS | - |
dc.title | A new anti-HIV flavonoid from glucoronide from Chrysanthemum marifolium | - |
dc.type | Article | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | PLANTA MEDICA, v.69, no.9, pp.859 - 861 | - |
dc.citation.title | PLANTA MEDICA | - |
dc.citation.volume | 69 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 859 | - |
dc.citation.endPage | 861 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.wosid | 000186249500016 | - |
dc.identifier.scopusid | 2-s2.0-0242288801 | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | IMMUNODEFICIENCY-VIRUS TYPE-1 | - |
dc.subject.keywordPlus | C-13 NMR | - |
dc.subject.keywordPlus | INTEGRASE | - |
dc.subject.keywordPlus | GLYCOSIDES | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | INHIBITORS | - |
dc.subject.keywordPlus | MORIFOLIUM | - |
dc.subject.keywordPlus | FLOWERS | - |
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