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dc.contributor.authorChoo, HYP-
dc.contributor.authorChoi, S-
dc.contributor.authorRyu, CK-
dc.contributor.authorKim, HJ-
dc.contributor.authorLee, IY-
dc.contributor.authorPae, AN-
dc.contributor.authorKoh, HY-
dc.date.accessioned2024-01-21T08:45:32Z-
dc.date.available2024-01-21T08:45:32Z-
dc.date.created2021-09-03-
dc.date.issued2003-05-01-
dc.identifier.issn0968-0896-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138583-
dc.description.abstractThe 3D-QSAR study of quinolinediones which showed potent inhibitory effect on the acetylcholine induced vaso-relaxation of rat aorta with the endothelium was conducted by CoMSIA. The statistical result, cross-validated q(2) (0.741) and r(2) (0.960) values, gave reliability to the prediction of inhibitory activity of this series. (C) 2003 Elsevier Science Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectNITRIC-OXIDE SYNTHASE-
dc.subjectPOTENT INHIBITORS-
dc.subjectLY83583-
dc.titleQSAR study of quinolinediones with inhibitory activity of endothelium-dependent vasorelaxation by CoMSIA-
dc.typeArticle-
dc.identifier.doi10.1016/S0968-0896(03)00045-2-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY, v.11, no.9, pp.2019 - 2023-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY-
dc.citation.volume11-
dc.citation.number9-
dc.citation.startPage2019-
dc.citation.endPage2023-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000182101000009-
dc.identifier.scopusid2-s2.0-0037401606-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusNITRIC-OXIDE SYNTHASE-
dc.subject.keywordPlusPOTENT INHIBITORS-
dc.subject.keywordPlusLY83583-
dc.subject.keywordAuthorQSAR-
dc.subject.keywordAuthorquinolinedione-
dc.subject.keywordAuthorCoMSIA-
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