An efficient synthesis of alpha-amino-delta-valerolactones by the Ugi five-center three-component reaction

Authors
Kim, YBPark, SJKeum, GJang, MSKang, SBLee, DHKim, Y
Issue Date
2002-09-20
Publisher
WILEY-V C H VERLAG GMBH
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.23, no.9, pp.1277 - 1284
Abstract
A novel approach to alpha-amino-delta-valerolactone derivatives 8 by the intramolecular Ugi five-center three-component reaction (U-5C-3CR) using the multifunctional starting material, L-pentahomoserine 5 is described.
Keywords
SOLUTION-PHASE SYNTHESIS; ARMSTRONGS CONVERTIBLE ISONITRILE; 4-COMPONENT CONDENSATION; MULTICOMPONENT REACTIONS; SOLID SUPPORT; LIBRARIES; ACIDS; ISOCYANIDES; PYRROLES; LACTAMS; SOLUTION-PHASE SYNTHESIS; ARMSTRONGS CONVERTIBLE ISONITRILE; 4-COMPONENT CONDENSATION; MULTICOMPONENT REACTIONS; SOLID SUPPORT; LIBRARIES; ACIDS; ISOCYANIDES; PYRROLES; LACTAMS; multicomponent reactions; combinatorial chemistry; Ugi reaction; L-pentahomoserine; glycolaldehyde dimer
ISSN
0253-2964
URI
https://pubs.kist.re.kr/handle/201004/139204
Appears in Collections:
KIST Article > 2002
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