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dc.contributor.authorOh, CH-
dc.contributor.authorCho, HW-
dc.contributor.authorBaek, D-
dc.contributor.authorCho, JH-
dc.date.accessioned2024-01-21T10:07:47Z-
dc.date.available2024-01-21T10:07:47Z-
dc.date.created2022-01-10-
dc.date.issued2002-09-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/139249-
dc.description.abstractThe synthesis of a new series of 1beta-methylcarbapenems having the substituted thiazolopyrrolidine moiety is described. Their in vitro antibacterial activities against both Gram-positive including, MRSA and Gram-negative bacteria were tested and the effect of substituent on the thiazole ring was investigated. A particular compound (28c) having 4-amide substituted thiazole moiety showed the most potent antibacterial activity. (C) 2002 Published by Editions scientifiques et medicales Elsevier SAS.-
dc.languageEnglish-
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER-
dc.subjectCARBAPENEM-
dc.titleSynthesis and antibacterial activity of 1 beta-methyl-2-(5-substituted thiazolo pyrrolidin-3-ylthio)carbapenem derivatives-
dc.typeArticle-
dc.identifier.doi10.1016/S0223-5234(02)01397-1-
dc.description.journalClass1-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.37, no.9, pp.743 - 754-
dc.citation.titleEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY-
dc.citation.volume37-
dc.citation.number9-
dc.citation.startPage743-
dc.citation.endPage754-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000178696500004-
dc.identifier.scopusid2-s2.0-0036753607-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusCARBAPENEM-
dc.subject.keywordAuthor1 beta-methylcarbapenem-
dc.subject.keywordAuthorantibacterial activity-
dc.subject.keywordAuthorsubstituent effect-
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