DSpace at KISTKIST Article2001

Full metadata record

DC Field Value Language
dc.contributor.authorKim, YS-
dc.contributor.authorKim, KM-
dc.contributor.authorSong, R-
dc.contributor.authorJun, MJ-
dc.contributor.authorSohn, YS-
dc.date.accessioned2024-01-21T11:34:25Z-
dc.date.available2024-01-21T11:34:25Z-
dc.date.created2021-09-04-
dc.date.issued2001-12-
dc.identifier.issn0162-0134-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/140007-
dc.description.abstractA new series of quinolone-platinum(II) conjugates, [Pt(Q'-NH2)(dmso)X-2] and cis-[Pt(Q"-en)X-2], where Q' and Q" are quinolones (flumequine, nalidixic acid or oxolinic acid) linked to monodentate and bidentate amine ligands, respectively, and X-2 is Cl-2 or 1,1-cyclobutanedicarboxy late, have been synthesized with the aim of examining the synergetic antitumor activity of quinolone intercalation and platinum(II) chelation. The complexes were characterized by elemental analyses and IR and multinuclear (H-1 and Pt-195) NMR spectroscopies, and then subjected to in vitro and in vivo bioassays using the leukemia L1210 cell line. (C) 2001 Elsevier Science B.V. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE INC-
dc.subjectPLATINUM COMPLEXES-
dc.subjectANTHRAQUINONE INTERCALATORS-
dc.subjectCRYSTAL-STRUCTURE-
dc.subjectDNA GYRASE-
dc.subjectSERIES-
dc.subjectLIGANDS-
dc.subjectAGENTS-
dc.subjectCYTOTOXICITY-
dc.subjectINHIBITION-
dc.subjectMECHANISM-
dc.titleSynthesis, characterization and antitumor activity of quinolone-platinum(II) conjugates-
dc.typeArticle-
dc.identifier.doi10.1016/S0162-0134(01)00345-2-
dc.description.journalClass1-
dc.identifier.bibliographicCitationJOURNAL OF INORGANIC BIOCHEMISTRY, v.87, no.3, pp.157 - 163-
dc.citation.titleJOURNAL OF INORGANIC BIOCHEMISTRY-
dc.citation.volume87-
dc.citation.number3-
dc.citation.startPage157-
dc.citation.endPage163-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000172909800005-
dc.identifier.scopusid2-s2.0-0035197497-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Inorganic & Nuclear-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusPLATINUM COMPLEXES-
dc.subject.keywordPlusANTHRAQUINONE INTERCALATORS-
dc.subject.keywordPlusCRYSTAL-STRUCTURE-
dc.subject.keywordPlusDNA GYRASE-
dc.subject.keywordPlusSERIES-
dc.subject.keywordPlusLIGANDS-
dc.subject.keywordPlusAGENTS-
dc.subject.keywordPlusCYTOTOXICITY-
dc.subject.keywordPlusINHIBITION-
dc.subject.keywordPlusMECHANISM-
dc.subject.keywordAuthorquinolone-
dc.subject.keywordAuthorplatinum-
dc.subject.keywordAuthorantitumor agents-
Appears in Collections:
KIST Article > 2001
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML
Show Simple Item Record

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE