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EFFICIENT SYNTHESIS OF AN EPOXY ALCOHOL, A KEY INTERMEDIATE FOR LTA4 SYNTHESIS

Authors
PARK, H; LEE, YS; SHIM, SC
Issue Date
1992-10-20
Publisher
KOREAN CHEMICAL SOC
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.13, no.5, pp.551 - 553
Abstract
An efficient and very short synthesis of epoxy alcohol 5, a key intermediate for leukotriene synthesis, was described. The key reaction involves the regioselective benzylidene acetal formation from methyl 5,6,7-trihydroxyheptanoate 1.
Keywords
ACID; LEUKOTRIENES; SELECTIVITY; ESTER; ACID; LEUKOTRIENES; SELECTIVITY; ESTER
ISSN
0253-2964
URI
https://pubs.kist.re.kr/handle/201004/146369
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KIST Article > Others
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