Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | KANG, HY | - |
dc.contributor.author | PAE, AN | - |
dc.contributor.author | KOH, HY | - |
dc.contributor.author | CHANG, MH | - |
dc.date.accessioned | 2024-01-21T23:46:56Z | - |
dc.date.available | 2024-01-21T23:46:56Z | - |
dc.date.created | 2022-01-10 | - |
dc.date.issued | 1991-02-20 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.uri | https://pubs.kist.re.kr/handle/201004/146835 | - |
dc.description.abstract | A series of compounds, N-(2-substituted-1-carboxy)vinylazetidinones were successfully synthesized in order to test the hypothesis that biological activities of beta-lactam antibiotics could be attributed to the smooth flow of electrons after a nucleophilic attack at the carbonyl carbon in the beta-lactam ring. After introduction of aminothiazolylacetamido group at 3-position of the azetidinones, their biological activities were evaluated. Their low activities led to the conclusion that the smooth electron flow in beta-lactams in not the sufficient source for the biological activities. | - |
dc.language | English | - |
dc.publisher | KOREAN CHEMICAL SOC | - |
dc.subject | LACTIVICIN | - |
dc.subject | PENEMS | - |
dc.title | SYNTHESIS AND BIOLOGICAL EVALUATIONS OF N-(2-SUBSTITUTED-1-CARBOXYL) VINYLAZETIDINONES - A STUDY ON THE ESSENTIAL STRUCTURAL ELEMENT FOR BIOLOGICAL-ACTIVITIES OF BETA-LACTAM ANTIBIOTICS | - |
dc.type | Article | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.12, no.1, pp.75 - 79 | - |
dc.citation.title | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 75 | - |
dc.citation.endPage | 79 | - |
dc.description.journalRegisteredClass | scie | - |
dc.identifier.wosid | A1991FA54600021 | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | LACTIVICIN | - |
dc.subject.keywordPlus | PENEMS | - |
dc.subject.keywordAuthor | azetidinones | - |
dc.subject.keywordAuthor | biological activities | - |
dc.subject.keywordAuthor | β -lactam antibiotics | - |
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