Heterostructure Cu2O/Ag nanowires for high-performance non-enzymatic glucose sensors

Abstract

Non-enzymatic glucose sensors have gained significant attention as promising alternatives to address the limitations associated with enzyme-based sensors. Numerous non-enzymatic glucose sensors have demonstrated effective, non-invasive blood glucose monitoring through the analysis of human body fluids such as urine, saliva, and sweat. In this study, Cu2O/Ag nanowires (NWs) nanocomposites were in situ fabricated as electrode materials for non-enzymatic glucose sensors. To enhance the electrocatalytic performance, Cu2O/Ag NWs nano-composites with a distinctive pepero-shaped morphology were synthesized using varied copper precursor ratios, facilitating a systematic investigation of Cu2O content on glucose detection. The results reveal that the CA-2 electrode material exhibits outstanding electrocatalytic performance for glucose detection, with sensitivity ranges of 10-100 nM and 1 mu M-1 mM, achieving sensitivities of 22,099 and 1474 mu A mM-1 cm-2, respectively, and a detection limit of 3.29 nM. Additionally, this material has shown high efficiency in detecting glucose in urine, highlighting its excellent detection capabilities.