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dc.contributor.authorCho, HW-
dc.contributor.authorOh, CH-
dc.contributor.authorLee, JS-
dc.contributor.authorLee, SC-
dc.contributor.authorChoi, JH-
dc.contributor.authorCho, JH-
dc.date.accessioned2024-01-21T08:05:34Z-
dc.date.available2024-01-21T08:05:34Z-
dc.date.created2021-09-03-
dc.date.issued2003-11-
dc.identifier.issn0365-6233-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138128-
dc.description.abstractThe synthesis of a new series of 2-alkyl-4-pyrrolidinylthio-b-methylcarbapenems containing the substituted heteroaromatic moieties is described. Their in vitro antibacterial activities against both gram-positive and gram-negative bacteria were tested. The effect of substituents on the nitrogen atoms at heteroaromatic rings was investigated. Particular compounds (14b, 14c) containing 3-methyl- and 3,5-dimethylpyrazolethio substituted moiety showed the most potent antibacterial activity.-
dc.languageEnglish-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subject1-BETA-METHYLCARBAPENEM-
dc.subjectTHIENAMYCIN-
dc.subjectANTIBIOTICS-
dc.subjectFR21818-
dc.titleSynthesis and antibacterial activities of 4-pyrrolidinylthio carbapenems: Containing heteroaromatics as a side chain-
dc.typeArticle-
dc.identifier.doi10.1002/ardp.200300728-
dc.description.journalClass1-
dc.identifier.bibliographicCitationARCHIV DER PHARMAZIE, v.336, no.11, pp.495 - 503-
dc.citation.titleARCHIV DER PHARMAZIE-
dc.citation.volume336-
dc.citation.number11-
dc.citation.startPage495-
dc.citation.endPage503-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000187229900001-
dc.identifier.scopusid2-s2.0-0348108047-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlus1-BETA-METHYLCARBAPENEM-
dc.subject.keywordPlusTHIENAMYCIN-
dc.subject.keywordPlusANTIBIOTICS-
dc.subject.keywordPlusFR21818-
dc.subject.keywordAuthorcarbapenems-
dc.subject.keywordAuthorantibacterials-
dc.subject.keywordAuthorDHP-I stability-
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